Here are the relevant data sheets:
Manufacturer: https://neoconix.com/wp-content/uploads/AS-000031-XBM-X-Beam-Product-Spec-Rev-D.pdf (this might not be the exact product Framework uses, but it’s the closest I could find)
The manufacturer says that it’s rated for 50 cycles (I assume this is for the release model of the connector) and disassembly definitely requires removing the keyboard and removing at least 2 screws, so it’s probably not something you want to do often. Yes, it looks like it’s more for upgrading or occasional swaps and less for “lets plug the GPU in when I get home”.