@Rachel_Is_Not My current scheme works pretty well for me, but you’re right that it can’t handle end+dn since dn would be interpreted as pgdn. You could add a hotkey that interprets ctrl+] to mean end+dn, but it’s true that we’re starting to run out of easy, one-handed combos at this point!
I wanted to suggest again that framework add a bios option to allow right-alt to be interpreted as fn, though alt+shift+end+down is also a pretty awkward combo! (Edit: Oops… and that also doesn’t solve the problem of fn+dn being interpreted as pgdn!)