Honestly, and this is my approach to all distros - if it’s working and not going to be outdated/unsupported soon, I leave my working installs alone. I have a very happy install of Fedora 37 on a personal machine even though I work on Fedora 38 for example.
That said, we have not had time to properly vet 21.2 yet for community level compatibility. May be fine, outside of the known issues list here (some of which would give me pause).
But it “should” be fine. Just remember, backup first before trying anything and as always, clean installs always have a higher success rate than an upgrade path in my experience. Some will debate this, I’ve witnessed for over a decade as fact.
Tltr: If you feel strongly about upgrading and wish to do so, consider everything above and backup, backup and backup.