If you want to get I2C for your own Mainboard-based projects, you can use a RP2040 board, but you can also get I2C out of a spare HDMI card, provided you run Linux!
All you need is the HDMI card (or any other USB-C to HDMI adapter) and a HDMI breakout; use pins SDA, SCL, 5V and GND. Add pullups from SDA and SCL to 5V (1.8K-10K range pullups). The resulting bus will be 5V-referenced, use a level shifter if you need 3.3V, or maybe do pullups to 3.3V. You also need to pull HDMI HPD to 5V, same 1.8K-10K range.
On the Linux side, you need to
modprobe i2c-dev. Use
i2cdetect -l to see which I2C buses are exposed to userspace. It will be one of the
AUX USBC1/DDI TC1/PHY TC buses in the list - run
i2cdetect on all four and see which one detects your device. You can then use libraries like
python-smbus to interact with your I2C stuff!
I will also be selling a touchpad I2C port breakout soon, but, that I2C is EC-connected and isn’t quite exposed to the userspace… I think?