TLP per AMD themselves, is not recommended if you want the full benefits of battery life. I know this might not be what you expected to hear, but ideally you are using the defaults that come with your distro or with DIY distros, tuneD. Using the power profiles GUI and battery save for battery mode.
Now, that said, if you are dead set on using TLP and understand AMD suggests this is not going to help, you will want to disable your existing power profile configuration (tuneD or on older distros, PPD)