One thing I’ve noticed on the Framework 16 is that if I’m using the device where there isn’t much support underneath the laptop, such as on my lap in bed instead of on a desk, then any pressure on the left palm rest has the potential to either click the left mouse button or lock it into the clicked position once I do actually click. This is a mechanical behavior that results in physical clicks to the trackpad. This can make interactions slightly irksome and accommodating the limitation isn’t as comfortable as relaxing my arms.
On the bright side, it encourages me to further ditch the cursor on my install of i3.
Someone appears to have reported the same issue for the Framework 13:
While this post talks about some software related stuff, I suspect this user is also seeing the mechanical issue I described.