12gen Framework (3rd batch i7-1280p).
Today I noticed that USB 3-3 (bottom right when viewed from above) wasn’t working. Only until I unplugged and reinserted the card did it start to work. After some time, I tried again and it wasn’t working again. Again, after unplugging and reinserting the card did it start to work.
The same behavior is observed while sitting in the BIOS.
I tried a different USB-A expansion card in the same slot, and the problem seems to be unique to the slot, not the card itself.