For learning PCB design, honestly, just youtube is enough to get started. I’d recommend KiCad. It’s free, open source, and not limited like free versions of commercial software can be.
I haven’t run into anyone creating a similar audio + usb project. Just some people saying they’d like such a card. There are projects such as dual USB-C port, dual USB-A, dongle + USB-A, dongle hider, etc. In varying states of completeness.
The dongle + USB-A card project might be a useful starting place for building the card you want. As it already contains a small usb hub chip, usb-c port, usb-a port. You can rearrange things, then add the audio components. I do believe the design is open source.