What's stopping me from buying a Framework 16

Welcome to the forum

Just want to check, this is the one you saw?

That’s the furthest along project I’ve come across for touchpad at least.

If you like buttons on the bottom, I’ve never tried it, but I imagine you might be able to have the touchpad driver swap input directions so that you can mount the touch pad buttons down. If you’re using a Clevo, I suspect you’re on linux.