The FW13 thread for Guix is here:
I haven’t tried Guix with the 7040 series yet (was running 11th gen Intel before), as that would probably be closest to any confirmation whether it will work with the FW16 before it starts shipping. I’ll save this thread and update if I try it on my FW13 AMD.
Using the nonguix channel and non-libre kernel will definitely be required since the amdgpu driver has firmware blobs. I assume likewise for the RZ616/mt7922 wireless card.