Since it may be relevent or compound to the issue, here is my thread where I have similar dis/re-connect issue with ssd expansion cards.
I have recently managed to get 1 full day without a single disconnect/reconnect after changing a power-management/performance setting in the bios (of the framework) off of max-battery. Normally I only get a few minutes and 3 hrs max.
Its a bit early to say I found the source and workaround for my issue, but seems promising. Let me know if yours is set to max-batery atm, and if changing it away from that seems to solve the issue for you as well. (or if it seems unrelated)
Trying to get a better idea of my issue and its STR. Hoping we are experiencing the same problem since the core symptom (unexpected usb disconnect/reconnect event of a plugged in device) is the same.