Yes.
Yeah, they posted a video here Framework Gaming Handheld Video!
But I haven’t seen them share details on the build. Some touchscreens use usb for the touch portion. If it’s usb and breaks that out to a separate connector, then you can connect it to any available usb port. Besides the normal 4 usb ports on the sides, a Framework-13 has a couple internal usb connections. The webcam and the fingerprint reader have usb connections.