Cutting off power to expansion cards while powered off

Hi there,
Does anyone know if it is possible to cut off power passing trough the expansion cards when the computer is sleeping/hibernating/powered off?
Living in a tropical climate, I am using a cooling pad plugged in directly into a USB port and my problem is that it never shuts off unless I unplug it.
I’ve checked in the BIOS but couldn’t find anything on the subject.

There are ways to power off usb ports from Linux. I do this on the raspberry pi connected to my 3d printer so that it doesn’t back-power the printer when it is off. In that case I use this tool. I haven’t tried it on Framework, but many motherboards already support the feature.

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