@2disbetter First off, that is a SWEET ride! Very cool. As per your question, the case does a very good job keeping the Framework laptop secure within it. It’s a nice snug fit. That being said, the edges/seams don’t have very much padding, so they won’t offer much vibration isolation. If the case vibrates, the laptop will as well. I tried shaking mine around in the case to see if it would be a good solution, and I can’t say for sure if would or wouldn’t. I’d have no hesitation saying yes in a backpack, but the road vibrations in your vehicle would probably be problematic over time. The flats are very well padded, but the foam is firm, and would transfer vibrations most likely as well. The case seems best for dings and bumps, not for sustained vibrations.